Week 5 - Paying a visit to the desert in Week 5, the San Francisco 49ers would look to end their two-game skid against an NFC Western Division foe, but would have their work cutout for them against an undefeated Arizona Cardinals (4-0) team. With quarterback Jimmy Garoppolo out with a calf injury he suffered during the first half of the Week 4 loss to Seattle, rookie QB Trey Lance who was selected third overall in the 2021 NFL Draft just five months earlier, would get the nod in Jimmy G's place. But even before Lance took the field to make his first career start, the young signal-caller received word that he would be thrusted into the lineup without arguably his best target in tight-end George Kittle who was ruled out of Sunday's game and placed on Injured Reserve on Saturday with a calf injury that he sustained in Week 1. With Kittle on the shelf for at least the next three games, coach Kyle Shanahan would need more production from Deebo Samuel who entered Week 5 leading all receivers in receiving yards.
Receiving the ball to begin the game, the 49er offense appeared to be in good hands after the first two plays as Lance showed his mobility with a 14-yard scramble, followed by a 16-yard strike to fullback Kyle Juszczyk for back-to-back first downs. But just two plays later, the drive would go up in flames as Lance airmailed a pass intended for Travis Benjamin that was intercepted by Cardinals safety Budda Baker. Like San Francisco prior to the turnover, the Arizona offense would have no problem moving the football as they cashed in on the interception with a touchdown on their first possession as running back James Connor rushed into the end zone from a yard out. In an early 7-0 hole, coach Shanahan's offense would face a number of 4th down situations where he elected to go for it, including on their second and third possessions. After failing to convert on a 4th and 2 run by Lance, the offense gave it another go one possession later. Pinned back near their own end zone at the San Francisco 6, the 49er offense would march all the way to the 1-yardline before facing another gutsy 4th down decision which ended in Lance being stood up at the goal line for another turnover on downs.
After adding a Matt Prater field goal to take a 10-0 lead, the Cardinals would attempt to increase their lead by way of the field goal just before the half with a 61-yard attempt that sailed wide-right. Opening the second half on defense, San Francisco held Arizona to their first set of back to back three and outs of the season to start the third quarter. Seeking their first trip to the end zone, the 49ers would get a big play from receiver Brandon Aiyuk who hauled in a 26-yard grab that turned into a 41-yard gain following an unnecessary roughness penalty against Arizona. Several plays later, the 49ers would finally strike pay dirt on a 13-yard toss to Deebo Samuel. San Francisco would have a chance to take their first lead of the game after forcing another Arizona punt, but another failed attempt on 4th and 1 near midfield would result in their third turnover on downs of the afternoon as Juszczyk took a direct-snap that proved ineffective. The Niners would get another shot at taking the lead when cornerback Dontae Johnson stripped running back Chase Edmonds of the ball on the Cardinals' following possession. But San Francisco's fourth and final turnover on downs would halt those hopes as Lance's pass on 4th and 4 was tipped at the line of scrimmage by Arizona's J.J. Watt.
Having kept DeAndre Hopkins relatively quiet for most of the afternoon, Cardinals QB Kyler Murray waited until the last half of the fourth quarter to get his best receiver more involved. Hopkins who is among the game's elite at the wide-out position and is without a doubt the best receiver on his team, passed another Cardinals great in Larry Fitzgerald for most receptions (764) by a player prior to their 30th birthday in NFL history. Among those receptions were a pair of grabs on consecutive plays, including a 30 yard catch that setup shop for the back-shoulder toss into the end zone for the touchdown on the very next play, also to Hopkins. Lance and company would show no signs of quitting as they would get a 47-yard field goal from the latest 49ers addition in kicker Joey Slye, making it a one-score game again at 17-10. Unfortunately for the Niners who were in need of a stop on defense with less than five minutes to go, the Cardinals converted on a pair of first downs that allowed Arizona head coach Kliff Kingsbury to run out the clock and seal the win.
While it wasn't the end result that San Francisco wanted, there were positives on both sides of the ball to be taken from the loss. To their credit, the 49er defense managed to make Kyler Murray look rather pedestrian after having put up MVP-like numbers through the first four weeks of the season. Holding him to just 240 yards of total offense and one touchdown, San Francisco did have some success applying pressure while sacking him twice. Though it's usually Murray who causes fits and torches opposing defenses on the ground with his legs, the first overall pick of the 2019 NFL Draft was outdone in that department by San Francisco's Trey Lance. The 49ers' duel-threat QB rushed for a game-high 89 yards on 16 carries, the fourth-highest total for a QB making his first career start (Lamar Jackson, Jalen Hurts and Randall Cunningham are the others). However, Murray did outgain Lance in passing yards, 239 to 192, respectively. After winning their first two games of the season, both on the road, Kyle Shanahan's 49ers have now lost three in a row, dropping to 2-3 on the year. Meanwhile, the Cardinals remain as the last of the NFL's undefeated at 5-0 for the first time since 1974 when they were the St. Louis Cardinals.
With his family in attendance, the big stage didn't necessarily appear to be too big for the 21-year old Lance, but he didn't have a whole lot working for him in his first career start either. Even without his first-string tight-end, the receivers Lance did have to throw to on Sunday didn't do him any favors as there were a number of dropped balls, and the many penalties only made things worse. It's more than obvious Lance oozes with raw talent that just needs to be honed before Shanahan can fully release his unrefined specimen, my biggest knock on the rookie is his rifle of an arm. It's both a blessing and a curse as Lance was able to zing a number of passes down the field with ease, but also had a little too much heat on other passes that were over or underthrown. When also factoring in his mobility to go along with his cannon of an arm, Lance reminded me a lot of Colin Kaepernick at times and that's not a bad thing. With his first professional start finally out of the way, Lance will learn from the experience and now has something to expand upon, whether that be again this season or in 2022.
Week 7 Preview: After a BYE Week in Week 6, the 49ers will return home in Week 7 to face Carson Wentz and the Indianapolis Colts (1-4). Like San Francisco, Indy is off to a start they did not foresee and are coming off a Monday Night loss in which they blew a 19-point lead on the road to Baltimore. In his first season with the Colts, QB Carson Wentz is coming off his best performance of the season after throwing for 402 yards and a pair of touchdowns, despite being out-dueled by the Ravens' Lamar Jackson. Facing former 49ers first round pick DeForest Buckner for the first time since trading him to the Colts for a first round pick a year ago, Niners head coach Kyle Shanahan is unsure who his quarterback will be come Week 7 as Garoppolo is working his way back from injury, and Trey Lance reportedly suffered a knee sprain in Sunday's loss to the Cardinals. However, Shanahan has mentioned if Jimmy G is healthy in time for gameday, he will be under center, regardless of Lance's status. While the question at quarterback remains unanswered at this time, there's no denying that the 49ers continue to have unbelievably bad luck with the injury bug.
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